In a skillet over medium heat, add the ground beef. Cook until browned, breaking it apart as it cooks.
Once cooked, drain any excess fat and sprinkle the onion powder, garlic powder, salt, and pepper evenly over the beef. Stir to combine, cooking for an additional minute to enhance the flavors.
In a small bowl, mix together the mayonnaise, ketchup, mustard, and dill pickle relish to create the special sauce. Set aside.
Lay out the large lettuce leaves on a clean surface. These will serve as your wraps.
Spoon a generous amount of the seasoned ground beef mixture into each lettuce leaf.
Top the beef with shredded cheddar cheese, diced tomatoes, and chopped onions.
Drizzle the special sauce over the top of each lettuce wrap.
If desired, sprinkle sesame seeds on top for an extra crunch and a touch of flavor.
Fold the sides of the lettuce over the filling to create a wrap, and enjoy!
Notes
Feel free to customize the toppings to your liking.
Keyword beef, Big Mac, healthy, lettuce wraps, low carb